The Biker Mice from Mars are on a quest to get hold of the one thing that can save Mars, their home planet, from total destruction the Regenerator, but they are not the only ones who want this powerful item Hairball, leader of the ruthless feline race the Catatonians, and Ronald Rump, evil corporate land developer want the Regenerator for their own evil purposes. They will throw everything they have at our heroes to acquire it, but the Biker Mice are not alone they have friends throughout the solar system to help them when the going gets rough.